Here are the week 12 picks from Clay Travis as found on Outkick.com.
| Florida State + 35 vs Clemson |
| Vanderbilt vs Florida Over 67.5 |
| Indiana + 21 vs Ohio State |
| Alabama vs Kentucky Under 57.5 |
| NC State vs Liberty Over 66.5 |
| Arkansas vs LSU Over 63.5 |
| Maryland -6.5 vs Michigan State |
| Mississippi State + 24.5 vs Georgia |
| Missouri -6.5 vs South Carolina |
| Utah + 2.5 vs Southern Cal |
| Auburn -10 vs Tennessee |