Here’s the week 2 picks from the Barstool Sports crew.
Dave Portnoy:
| Date | Pick |
| 9/6/19 | Boise State -12 vs Marshall |
| 9/6/19 | Boise State vs Marshall Over 56.5 |
| 9/6/19 | Arizona State -36 vs Sacramento State |
| 9/7/19 | Arkansas + 6.5 vs Ole Miss |
| 9/7/19 | Florida Atlantic vs UCF Over 68 |
| 9/7/19 | Kentucky -14.5 vs Eastern Michigan |
| 9/7/19 | Connecticut vs Illinois Over 59.5 |
| 9/7/19 | Texas + 6.5 vs LSU |
| 9/7/19 | Texas vs LSU Over 55 |
| 9/7/19 | North Carolina + 5 vs Miami (FL) |
| 9/7/19 | Colorado + 3.5 vs Nebraska |
| 9/7/19 | Virginia Tech -28 vs Old Dominion |
| 9/7/19 | Iowa -20 vs Rutgers |
| 9/7/19 | Georgia Tech -6 vs South Florida |
| 9/7/19 | Syracuse + 2 vs Maryland |
| 9/7/19 | Texas A&M + 17.5 vs Clemson |
| 9/6/19 | Rice + 18.5 vs Wake Forest |
| 9/7/19 | Michigan State -17 vs Western Michigan |
Dan Katz:
| Date | Pick |
| 9/7/19 | Army + 22.5 vs Michigan |
| 9/7/19 | Eastern Michigan + 14.5 vs Kentucky |
| 9/7/19 | Illinois -20 vs Connecticut |
| 9/7/19 | Texas + 6.5 vs LSU |
| 9/7/19 | Miami (FL) -5 vs North Carolina |
| 9/7/19 | Oregon -24 vs Nevada |
| 9/7/19 | Ohio + 6 vs Pittsburgh |
| 9/7/19 | Hawaii vs Oregon State Over 78.5 |
| 9/7/19 | San Diego State + 7.5 vs UCLA |
| 9/7/19 | Stanford + 1 vs Southern Cal |
| 9/7/19 | Tulane + 18 vs Auburn |
| 9/7/19 | Vanderbilt + 7 vs Purdue |
| 9/6/19 | Rice vs Wake Forest Over 55.5 |
| 9/7/19 | Michigan State vs Western Michigan Under 46.5 |
Rico Bosco:
| Date | Pick |
| 9/7/19 | Kansas State -23 vs Bowling Green |
| 9/7/19 | UCF -10 vs Florida Atlantic |
| 9/7/19 | Baylor -26.5 vs UTSA |
| 9/7/19 | Baylor vs UTSA Over 56.5 |
| 9/7/19 | Western Michigan + 16 vs Michigan State |