Here are the week 2 picks against the spread from the Yahoo Sports College podcast featuring Pat Forde, Dan Wetzel and Pete Thamel!
Pat Forde:
| Date | Pick |
| 9/12/20 | Louisville -11.5 vs Western Kentucky |
| 9/12/20 | Louisiana + 11.5 vs Iowa State |
| 9/12/20 | Florida State -12.5 vs Georgia Tech |
| 9/12/20 | Duke + 19.5 vs Notre Dame |
| 9/12/20 | Clemson -33.5 vs Wake Forest |
| 9/10/20 | Miami (FL) -14 vs UAB |
Dan Wetzel:
| Date | Pick |
| 9/12/20 | Iowa State -11.5 vs Louisiana |
| 9/12/20 | Florida State -12.5 vs Georgia Tech |
| 9/12/20 | Notre Dame -19.5 vs Duke |
| 9/12/20 | Kansas -6.5 vs Coastal Carolina |
| 9/12/20 | Clemson -33.5 vs Wake Forest |
| 9/10/20 | UAB + 14 vs Miami (FL) |
Pete Thamel:
| Date | Pick |
| 9/12/20 | North Carolina -23 vs Syracuse |
| 9/12/20 | Louisiana + 11.5 vs Iowa State |
| 9/12/20 | Florida State -12.5 vs Georgia Tech |
| 9/12/20 | Duke + 19.5 vs Notre Dame |
| 9/12/20 | Clemson -33.5 vs Wake Forest |
| 9/10/20 | UAB + 14 vs Miami (FL) |