Here are the picks from the Barstool College Pick’em podcast.
Dave Portnoy:
| Arizona + 11 vs Mississippi State |
| Oregon State -1 vs Fresno State |
| Fresno State vs Oregon State Over 60.5 |
| BYU -3.5 vs Baylor |
| BYU vs Baylor Over 53.5 |
| Nebraska vs Georgia Southern Over 62.5 |
| Stanford vs Southern Cal Over 66.5 |
| Oklahoma State -11.5 vs Arizona State |
| Oklahoma State vs Arizona State Over 57.5 |
| Connecticut + 23 vs Syracuse |
| Kentucky + 5 vs Florida |
| Texas Tech vs Houston Over 65.5 |
| Texas Tech -3 vs Houston |
| Iowa -3.5 vs Iowa State |
| Texas A&M -18.5 vs Appalachian State |
| Pittsburgh vs Tennessee Over 66 |
| Pittsburgh + 7 vs Tennessee |
| Alabama -20 vs Texas |
| Arkansas -9 vs South Carolina |
Dan Katz:
| Arizona + 11 vs Mississippi State |
| BYU vs Baylor Over 53.5 |
| Boston College + 3 vs Virginia Tech |
| Southern Cal -8 vs Stanford |
| Oklahoma vs Kent State Over 71 |
| Kentucky + 5 vs Florida |
| Iowa vs Iowa State Over 40.5 |
| UNLV + 12.5 vs California |
| Memphis -6 vs Navy |
| Texas A&M vs Appalachian State Under 52.5 |
| Charlotte vs Maryland Over 65.5 |
| Wisconsin vs Washington State Under 49 |
| Pittsburgh + 7 vs Tennessee |
| Pittsburgh vs Tennessee Over 66 |
| Georgia State + 7.5 vs North Carolina |
| Texas + 20 vs Alabama |
| Texas vs Alabama Over 64.5 |
| South Carolina + 9 vs Arkansas |
| Vanderbilt vs Wake Forest Over 66 |
| Kansas State vs Missouri Over 57 |
| Ohio + 24.5 vs Penn State |
| UCF vs Louisville Over 61.5 |
Rico Bosco:
| BYU -3.5 vs Baylor |
| BYU vs Baylor Over 53.5 |
| Southern Cal -8 vs Stanford |
| Kentucky + 5 vs Florida |
| UAB -6.5 vs Liberty |
| Iowa -3.5 vs Iowa State |
| Texas A&M vs Appalachian State Over 52.5 |
| Charlotte vs Maryland Over 65.5 |
| Washington State + 17 vs Wisconsin |
| Pittsburgh vs Tennessee Over 66 |
| Miami (FL) vs Southern Miss Over 54.5 |
| Texas vs Alabama Over 64.5 |
| South Carolina + 9 vs Arkansas |