Here are the week 12 picks from Sam Cooper and Nick Bromberg of Yahoo Sports fame.
Sam Cooper:
| Wyoming + 14 vs Boise State |
| Wyoming vs Boise State Under 44.5 |
| Iowa + 3 vs Minnesota |
| Illinois + 17.5 vs Michigan |
| Penn State -19 vs Rutgers |
| TCU -2.5 vs Baylor |
| Oregon + 1.5 vs Utah |
| Arkansas + 2.5 vs Ole Miss |
| Iowa State vs Texas Tech Under 47.5 |
| UCLA + 2.5 vs Southern Cal |
| Louisville vs NC State Under 45.5 |
Nick Bromberg:
| Army vs Connecticut Under 43.5 |
| Michigan -17.5 vs Illinois |
| TCU -2.5 vs Baylor |
| Utah -1.5 vs Oregon |
| Kansas + 9.5 vs Texas |
| Ole Miss -2.5 vs Arkansas |
| Massachusetts + 33.5 vs Texas A&M |
| Southern Cal -2.5 vs UCLA |