Here’s the week 5 picks from Clay Travis via his Outkick the Coverage blog.
| Date | Pick |
| 9/27/19 | California vs Arizona State Under 40 |
| 9/27/19 | Penn State -6.5 vs Maryland |
| 9/28/19 | Arkansas + 23 vs Texas A&M |
| 9/28/19 | UCF -42.5 vs Connecticut |
| 9/28/19 | Iowa vs MTSU Over 51.5 |
| 9/28/19 | Alabama -35 vs Ole Miss |
| 9/28/19 | Wisconsin -23.5 vs Northwestern |
| 9/28/19 | Washington -9.5 vs Southern Cal |
| 9/28/19 | Arizona vs UCLA Over 71 |
| 9/28/19 | Notre Dame -11 vs Virginia |