Here are the week 5 picks from the Barstool Sports College Pick’em Podcast.
Dave Portnoy:
| Date | Pick |
| 10/3/20 | Georgia -6.5 vs Auburn |
| 10/3/20 | SMU + 2.5 vs Memphis |
| 10/3/20 | Kentucky -6.5 vs Ole Miss |
| 10/3/20 | Missouri + 11 vs Tennessee |
| 10/3/20 | Cincinnati -21.5 vs South Florida |
Dan Katz:
| Date | Pick |
| 10/3/20 | Georgia -6.5 vs Auburn |
| 10/3/20 | Auburn vs Georgia Under 45 |
| 10/3/20 | Baylor -3 vs West Virginia |
| 10/3/20 | Memphis vs SMU Over 74 |
| 10/3/20 | Missouri + 11 vs Tennessee |
| 10/3/20 | Navy vs Air Force Under 46.5 |
| 10/3/20 | Oklahoma -7 vs Iowa State |
| 10/3/20 | Oklahoma vs Iowa State Over 63 |
| 10/3/20 | TCU vs Texas Over 62.5 |
| 10/3/20 | Clemson -28 vs Virginia |
| 10/3/20 | Virginia vs Clemson Over 55 |
Rico Bosco:
| Date | Pick |
| 10/3/20 | Baylor -3 vs West Virginia |
| 10/3/20 | SMU + 2.5 vs Memphis |
| 10/3/20 | Memphis vs SMU Over 74.5 |
| 10/3/20 | Oklahoma State -21 vs Kansas |
| 10/3/20 | TCU vs Texas Over 62.5 |
| 10/3/20 | Texas Tech vs Kansas State Over 64 |
| 10/3/20 | UAB -20.5 vs UTSA |
| 10/3/20 | Virginia Tech -7.5 vs Duke |