Here are the week 6 picks from the Yahoo Sports College podcast.
Pat Forde:
| Date | Pick |
| 10/10/20 | Florida -6 vs Texas A&M |
| 10/10/20 | Kansas State + 9 vs TCU |
| 10/10/20 | Clemson -14 vs Miami (FL) |
| 10/10/20 | Oklahoma -2.5 vs Texas |
| 10/10/20 | Georgia -12.5 vs Tennessee |
| 10/10/20 | North Carolina -5 vs Virginia Tech |
Dan Wetzel:
| Date | Pick |
| 10/10/20 | Florida -6 vs Texas A&M |
| 10/10/20 | Notre Dame -20.5 vs Florida State |
| 10/10/20 | Clemson -14 vs Miami (FL) |
| 10/10/20 | Oklahoma -2.5 vs Texas |
| 10/10/20 | Georgia -12.5 vs Tennessee |
| 10/10/20 | North Carolina -5 vs Virginia Tech |
Pete Thamel:
| Date | Pick |
| 10/10/20 | Florida -6 vs Texas A&M |
| 10/10/20 | Clemson -14 vs Miami (FL) |
| 10/10/20 | Texas + 2.5 vs Oklahoma |
| 10/10/20 | Georgia -12.5 vs Tennessee |
| 10/10/20 | Texas Tech + 12.5 vs Iowa State |
| 10/10/20 | North Carolina -5 vs Virginia Tech |