Here are the week 12 picks from Brady Quinn and Danny Kanell via their weekly appearance on CBS Sports HQ.
Brady Quinn:
| Notre Dame -21 vs Boston College |
| Notre Dame vs Boston College Under 45 |
| Maryland + 27.5 vs Ohio State |
| Maryland vs Ohio State Under 64.5 |
| North Carolina -21 vs Georgia Tech |
| North Carolina vs Georgia Tech Over 63.5 |
| Illinois + 18 vs Michigan |
| Michigan vs Illinois Under 42 |
| Rutgers + 19 vs Penn State |
| Rutgers vs Penn State Under 45 |
| Oklahoma -7.5 vs Oklahoma State |
| Oklahoma vs Oklahoma State Over 64.5 |
| TCU -2.5 vs Baylor |
| Baylor vs TCU Over 57.5 |
| Utah + 3 vs Oregon |
| Oregon vs Utah Over 61.5 |
| Kansas State -7.5 vs West Virginia |
| West Virginia vs Kansas State Under 55 |
| Arkansas + 2.5 vs Ole Miss |
| Arkansas vs Ole Miss Under 61 |
| Kentucky + 22.5 vs Georgia |
| Kentucky vs Georgia Under 49.5 |
| Arizona State + 8 vs Oregon State |
| Arizona State vs Oregon State Over 54 |
| Tennessee -21.5 vs South Carolina |
| South Carolina vs Tennessee Under 66 |
| Washington -31 vs Colorado |
| Washington vs Colorado Over 61.5 |
| LSU -14.5 vs UAB |
| LSU vs UAB Under 52.5 |
| Cincinnati -17 vs Temple |
| Temple vs Cincinnati Over 51 |
| UCF -16.5 vs Navy |
| UCF vs Navy Under 53 |
| Southern Cal -2.5 vs UCLA |
| UCLA vs Southern Cal Over 75.5 |
| NC State + 4 vs Louisville |
| Louisville vs NC State Over 45 |
| Louisiana + 24 vs Florida State |
| Florida State vs Louisiana Under 52 |
| Clemson -19 vs Miami (FL) |
| Clemson vs Miami (FL) Over 48 |
| SMU + 3 vs Tulane |
| Tulane vs SMU Over 65 |
Danny Kanell:
| Notre Dame -21 vs Boston College |
| Notre Dame vs Boston College Over 45 |
| Maryland + 27.5 vs Ohio State |
| Maryland vs Ohio State Over 64.5 |
| Georgia Tech + 21 vs North Carolina |
| North Carolina vs Georgia Tech Over 63.5 |
| Michigan -18 vs Illinois |
| Michigan vs Illinois Over 42 |
| Rutgers + 19 vs Penn State |
| Rutgers vs Penn State Over 45 |
| Oklahoma State + 7.5 vs Oklahoma |
| Oklahoma vs Oklahoma State Under 64.5 |
| Baylor + 2.5 vs TCU |
| Baylor vs TCU Under 57.5 |
| Oregon -3 vs Utah |
| Oregon vs Utah Under 61.5 |
| West Virginia + 7.5 vs Kansas State |
| West Virginia vs Kansas State Under 55 |
| Arkansas + 2.5 vs Ole Miss |
| Arkansas vs Ole Miss Under 61 |
| Kentucky + 22.5 vs Georgia |
| Kentucky vs Georgia Under 49.5 |
| Arizona State + 8 vs Oregon State |
| Arizona State vs Oregon State Under 54 |
| South Carolina + 21.5 vs Tennessee |
| South Carolina vs Tennessee Under 66 |
| Washington -31 vs Colorado |
| Washington vs Colorado Under 61.5 |
| UAB + 14.5 vs LSU |
| LSU vs UAB Under 52.5 |
| Cincinnati -17 vs Temple |
| Temple vs Cincinnati Over 51 |
| UCF -16.5 vs Navy |
| UCF vs Navy Over 53 |
| Southern Cal -2.5 vs UCLA |
| UCLA vs Southern Cal Under 75.5 |
| Louisville -4 vs NC State |
| Louisiana + 24 vs Florida State |
| Florida State vs Louisiana Under 52 |
| Clemson -19 vs Miami (FL) |
| Clemson vs Miami (FL) Over 48 |
| SMU + 3 vs Tulane |
| Tulane vs SMU Under 65 |