Week 10 2021: CFB Picks from the Barstool College Pick’em Podcast!
Dave Portnoy:
| Boise State + 5 vs Fresno State |
| Navy + 21 vs Notre Dame |
| Alabama -28.5 vs LSU |
| Alabama vs LSU Over 66 |
| Arizona + 12.5 vs California |
| Hawaii + 7 vs San Diego State |
| Iowa State vs Texas Over 60.5 |
| Kentucky 0 vs Tennessee |
| Kentucky vs Tennessee Over 57.5 |
| Maryland + 10 vs Penn State |
| Maryland vs Penn State Over 55 |
| Nebraska + 15 vs Ohio State |
| Wake Forest + 2.5 vs North Carolina |
| Ole Miss -10 vs Liberty |
| Ole Miss vs Liberty Over 67.5 |
| Purdue + 3 vs Michigan State |
| Wisconsin -12 vs Rutgers |
| Texas A&M vs Auburn Over 49.5 |
| Washington + 7 vs Oregon |
| West Virginia + 3 vs Oklahoma State |
| Stanford + 7.5 vs Utah |
Dan Katz:
| Navy + 21 vs Notre Dame |
| MTSU + 15 vs Western Kentucky |
| Alabama vs LSU Over 66 |
| Cincinnati -22.5 vs Tulsa |
| Pittsburgh -21 vs Duke |
| Georgia -38 vs Missouri |
| Kansas State -23.5 vs Kansas |
| Illinois + 14.5 vs Minnesota |
| Nebraska vs Ohio State Over 64.5 |
| North Carolina vs Wake Forest Over 76 |
| Purdue + 3 vs Michigan State |
| Wisconsin -13.5 vs Rutgers |
| Texas A&M -5 vs Auburn |
| Washington + 7 vs Oregon |
| Stanford vs Utah Over 52 |
| Louisiana -13 vs Georgia State |
| Kent State -3 vs Northern Illinois |
| Central Michigan + 9 vs Western Michigan |
| Ball State -20 vs Akron |
| Ohio + 7 vs Miami (OH) |
| Eastern Michigan + 10 vs Toledo |
Rico Bosco:
| Notre Dame vs Navy Over 47 |
| Air Force -2.5 vs Army |
| LSU + 28.5 vs Alabama |
| California -12.5 vs Arizona |
| Missouri + 38 vs Georgia |
| Kansas State -23.5 vs Kansas |
| SMU -5 vs Memphis |
| Ohio State -15 vs Nebraska |
| Purdue + 3 vs Michigan State |
| Houston -13 vs South Florida |
| Auburn + 5 vs Texas A&M |
| Texas State vs Louisiana Monroe Over 59.5 |
| Oregon -7 vs Washington |